Dental Implants Failure and Rejection Reasons

While rare, sometimes dental implants failure can occur is some instances. There are a number of different reason that dental implant rejection or failure can happen.
By understanding the cited causes for dental implants failure, you can make a better decision as to whether or not dental implants are right for you and your needs.
When it comes to dental implants failure, there is a higher risk of dental implant failure in the upper jaw.
There is a five percent increased chance of implant failure when an implant is put in a patient’s upper jaw when compared to implants that are placed in the lower jaw bone.
What’s more, in a yet to be explained issue, a person can have multiple dental implants where only a single implant fails and the remainder of the implants prove successful.
Researchers have yet to determine why such dental implant failures occur on occasion. There are however, existing theories for this type of dental implant rejection which point to the presence of bacteria within the patient’s jawbone at the time of the implant.
It is believed that the placement of an implant in a jawbone may cause bacteria to be distributed in the surrounding area of the mouth and that it has a baneful effect on the tissues inside the mouth.
Any implants that manage to escape contact with the unleashed bacteria remain intact while the implant that is affected by the existing bacteria ultimately fails.

How Do Periodontal Pathogens Contribute to Atherosclerosis?

HELSINKI, FINLAND -- June 12, 2007 -- Periodontitis and periodontal pathogens raise the risk of atherosclerosis and cardiovascular diseases (CVD) events through an increase in serum lipopolysaccharide (LPS), according to new research presented here at the 76th Congress of the European Atherosclerosis Society (EAS).


Periodontitis, an infection in tooth-supporting tissues, is recognised as an independent risk factor for CVD. However, the exact mechanism behind the association between periodontitis and CVD is not known.


"One of the basic hypotheses behind the mechanism for the association between periodontitis and CVD is endotoxemia caused by gram-negative periodontal pathogens, since they have an open access to circulation through bleeding gums," said lead investigator Pirkko Pussinen, PhD, adjunct professor, Institute of Dentistry, University of Helsinki, Helsinki, Finland.


LPS in the circulation is a potent activator of inflammatory cells leading to macrophage-derived foam cell formation, a hallmark of early atherosclerosis, and it has been hypothesised that an increase in serum LPS concentration might mediate the association between periodontitis and CVD, Dr. Pussinen explained. "However, this hypothesis has not been tested before," she said.


To investigate the association between the risk of incident CVD events and serum antibody levels to major periodontal pathogens, as well as total LPS concentration and various inflammatory markers, Dr. Pussinen and colleagues conducted a prospective case-cohort study involving a cohort of 6,051 people between 25 and 64 years of age, with a median follow-up of 10 years. During that time, 189 incident CVD events occurred. A stratified random sample (n=320) of the original cohort served as control.


The researchers found that a high combined antibody response to periodontal pathogens independently predicted incident CVD events, and high LPS concentration was also associated with increased CVD risk.


These results suggest that systemic exposure to periodontal pathogens or LPS induces systemic inflammation leading to increased risk for CVD, the researchers concluded. "We've also found that endotoxemia is especially harmful for subjects with a low HDL cholesterol concentration," Dr. Pussinen noted.


In view of these data, it is very important that practising clinicians pay attention to the oral health of their patients and refer them to see a dentist regularly, Dr. Pussinen suggested.